Genome sequence of an M3 strain of Streptococcus pyogenes reveals a large-scale genomic rearrangement in invasive strains and new insights into phage evolution.

@article{Nakagawa2003GenomeSO,
  title={Genome sequence of an M3 strain of Streptococcus pyogenes reveals a large-scale genomic rearrangement in invasive strains and new insights into phage evolution.},
  author={Ichiro Nakagawa and Ken Kurokawa and Atsushi Yamashita and Masanobu Nakata and Yusuke Tomiyasu and Nobuo Okahashi and Shigetada Kawabata and Kiyoshi Yamazaki and Tadayoshi Shiba and Teruo Yasunaga and Hideo Hayashi and Masahira Hattori and Shigeyuki Hamada},
  journal={Genome research},
  year={2003},
  volume={13 6A},
  pages={1042-55}
}
Group Astreptococcus (GAS) is a gram-positive bacterial pathogen that causes various suppurative infections and nonsuppurative sequelae. Since the late 1980s, streptococcal toxic-shock like syndrome (STSS) and severe invasive GAS infections have been reported globally. Here we sequenced the genome of serotype M3 strain SSI-1, isolated from an STSS patient in Japan, and compared it with those of other GAS strains. The SSI-1 genome is composed of 1,884,275 bp, and 1.7 Mb of the sequence is highly… CONTINUE READING
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