Genome sequence of a serotype M28 strain of group a streptococcus: potential new insights into puerperal sepsis and bacterial disease specificity.

@article{Green2005GenomeSO,
  title={Genome sequence of a serotype M28 strain of group a streptococcus: potential new insights into puerperal sepsis and bacterial disease specificity.},
  author={N. Michael Green and Shizhen Zhang and Stephen F Porcella and Michal J. Nagiec and Kent D. Barbian and Stephen B Beres and Rance B Lefebvre and James M. Musser},
  journal={The Journal of infectious diseases},
  year={2005},
  volume={192 5},
  pages={760-70}
}
Puerperal sepsis, a major cause of death of young women in Europe in the 1800s, was due predominantly to the gram-positive pathogen group A Streptococcus. Studies conducted during past decades have shown that serotype M28 strains are the major group A Streptococcus organisms responsible for many of these infections. To begin to increase our understanding of their enrichment in puerperal sepsis, we sequenced the genome of a genetically representative strain. This strain has genes encoding a… CONTINUE READING