Genome sequence of Streptococcus mutans UA159, a cariogenic dental pathogen.

  title={Genome sequence of Streptococcus mutans UA159, a cariogenic dental pathogen.},
  author={Dragana Ajdi{\'c} and William M. McShan and Robert E McLaughlin and Gorana Savi{\'c} and Jin Sook Chang and Matthew B. Carson and Charles Primeaux and Runying Tian and Steve M. Kenton and Honggui Jia and Shaoping Lin and Yudong Qian and Shuling Li and Hua Zhu and Fares Z. Najar and Hongshing Lai and J. White and B. A. Roe and Joseph J. Ferretti},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={99 22},
Streptococcus mutans is the leading cause of dental caries (tooth decay) worldwide and is considered to be the most cariogenic of all of the oral streptococci. The genome of S. mutans UA159, a serotype c strain, has been completely sequenced and is composed of 2,030,936 base pairs. It contains 1,963 ORFs, 63% of which have been assigned putative functions. The genome analysis provides further insight into how S. mutans has adapted to surviving the oral environment through resource acquisition… CONTINUE READING
Highly Influential
This paper has highly influenced a number of papers. REVIEW HIGHLY INFLUENTIAL CITATIONS