Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia.

@article{Lewis2003GenomeSM,
  title={Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia.},
  author={Cathryn M. Lewis and Douglas F. Levinson and Lesley H Wise and Lynn E. DeLisi and Richard E Straub and Iiris Hovatta and Nigel W. Williams and Sibylle G. Schwab and Ann E Pulver and Stephen V Faraone and Linda Brzustowicz and Charles A Kaufmann and David L. Garver and Hugh Malcolm Douglas Gurling and Eva Lindholm and Hilary Coon and Hans Moises and William Byerley and Sarah H. Shaw and Andrea Mes{\'e}n and Robin Sherrington and Francis Anthony O'Neill and Dermot Walsh and Kenneth S. Kendler and J. Ekelund and Tiina Paunio and Jouko L{\"o}nnqvist and L. Peltonen and Michael C O'Donovan and Michael J Owen and Dieter D B Wildenauer and Wolfgang Maier and Gerald Nestadt and J. L. Blouin and Stylianos E. Antonarakis and B. J. Mowry and Jeremy M. Silverman and Raymond R. Crowe and C. Robert Cloninger and Ming T. Tsuang and Dolores Malaspina and Jill M Harkavy-Friedman and Dragan M. Svrakic and Anne S. Bassett and Jennifer M Holcomb and Gursharan Kalsi and Andrew McQuillin and Jon Brynjolfson and Thordur Sigmundsson and Hannes P{\'e}tursson and Elena Jazin and T{\'o}mas Zo{\"e}ga and T{\'o}mas Helgason},
  journal={American journal of human genetics},
  year={2003},
  volume={73 1},
  pages={34-48}
}
Schizophrenia is a common disorder with high heritability and a 10-fold increase in risk to siblings of probands. Replication has been inconsistent for reports of significant genetic linkage. To assess evidence for linkage across studies, rank-based genome scan meta-analysis (GSMA) was applied to data from 20 schizophrenia genome scans. Each marker for each scan was assigned to 1 of 120 30-cM bins, with the bins ranked by linkage scores (1 = most significant) and the ranks averaged across… CONTINUE READING
Highly Influential
This paper has highly influenced 11 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 507 extracted citations

Psychosis and autism as diametrical disorders of the social brain.

The Behavioral and brain sciences • 2008
View 9 Excerpts
Highly Influenced

A note on generalized Genome Scan Meta-Analysis statistics

BMC Bioinformatics • 2004
View 6 Excerpts
Highly Influenced

Significant association of close homologue of L1 gene polymorphism rs2272522 with schizophrenia in Qatar.

Asia-Pacific psychiatry : official journal of the Pacific Rim College of Psychiatrists • 2013
View 2 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 66 references

Linkage analysis of schizophrenia to chromosome 15.

American journal of medical genetics • 2001
View 1 Excerpt
Highly Influenced

wide scan in multiplex pedigrees

PV Gejman, AR Sanders, JA Badner, Q Cao, J Zhang
Schizophr Res • 2001
View 2 Excerpts
Highly Influenced

Schizo - phrenia : a genome scan targets chromosomes 3 p and 8 p as potential sites of susceptibility genes

AE Pulver, VK Lasseter, +13 authors HH Kazazian
Am J Med Genet • 1995
View 1 Excerpt
Highly Influenced

Similar Papers

Loading similar papers…