Genome-scale profiling of histone H3.3 replacement patterns

  title={Genome-scale profiling of histone H3.3 replacement patterns},
  author={Yoshiko Mito and Jorja G. Henikoff and Steven Henikoff},
  journal={Nature Genetics},
Histones of multicellular organisms are assembled into chromatin primarily during DNA replication. When chromatin assembly occurs at other times, the histone H3.3 variant replaces canonical H3. Here we introduce a new strategy for profiling epigenetic patterns on the basis of H3.3 replacement, using microarrays covering roughly one-third of the Drosophila melanogaster genome at 100-bp resolution. We identified patterns of H3.3 replacement over active genes and transposons. H3.3 replacement… CONTINUE READING
Highly Influential
This paper has highly influenced 14 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
235 Citations
52 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 235 extracted citations


Publications referenced by this paper.
Showing 1-10 of 52 references

The profile of repeat-associated histone lysine methylation states in the mouse epigenome

  • Martens, J.H
  • EMBO J. 24,
  • 2005

Similar Papers

Loading similar papers…