Genome scaffolding with PE-contaminated mate-pair libraries

Abstract

Scaffolding is often an essential step in a genome assembly process, in which contigs are ordered and oriented using read pairs from a combination of paired-ends libraries and longer-range mate-pair libraries. Although a simple idea, scaffolding is unfortunately hard to get right in practice. One source of problem is so-called PE-contamination in mate-pair… (More)

Topics

7 Figures and Tables

Slides referencing similar topics