Genome rearrangement with gene families

  title={Genome rearrangement with gene families},
  author={David Sankoff},
  volume={15 11},
MOTIVATION The theory and practice of genome rearrangement analysis breaks down in the biologically widespread contexts where each gene may be present in a number of copies, not necessarily contiguous. In some of these contexts it is, however, appropriate to ask which members of each gene family in two genomes G and H, lengths lG and lH, are its true exemplars, i.e. which best reflect the original position of the ancestral gene in the common ancestor genome. This entails a search for the two… CONTINUE READING
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