Genome profiles of familial/bilateral and sporadic testicular germ cell tumors.

@article{Kraggerud2002GenomePO,
  title={Genome profiles of familial/bilateral and sporadic testicular germ cell tumors.},
  author={Sigrid Marie Kraggerud and Rolf I. Skotheim and Jadwiga Szymanska and Mette Eknaes and Sophie D Fossa and Anna Elisabeth Stenwig and P{\"a}ivi Peltom{\"a}ki and Ragnhild A. Lothe},
  journal={Genes, chromosomes & cancer},
  year={2002},
  volume={34 2},
  pages={168-74}
}
In order to investigate the genetics of testicular germ cell tumors (TGCTs), we examined 33 TGCTs, including 15 familial/bilateral and 18 sporadic tumors, using comparative genomic hybridization. The frequencies of the histological subtypes were comparable between the two groups. Gains of the whole or parts of chromosome 12 were found in 30 tumors (91%). Furthermore, increased copy number of the whole or parts of chromosomes 7, 8, 17, and X, and decreased copy number of the whole or parts of… CONTINUE READING