Genome phylogenetic analysis based on extended gene contents.

  title={Genome phylogenetic analysis based on extended gene contents.},
  author={Xun Gu and Hongmei Zhang},
  journal={Molecular biology and evolution},
  volume={21 7},
With the rapid growth of entire genome data, whole-genome approaches such as gene content become popular for genome phylogeny inference, including the tree of life. However, the underlying model for genome evolution is unclear, and the proposed (ad hoc) genome distance measure may violate the additivity. In this article, we formulate a stochastic framework for genome evolution, which provides a basis for defining an additive genome distance. However, we show that it is difficult to utilize the… CONTINUE READING

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