Genome packaging in influenza A virus.

@article{Hutchinson2010GenomePI,
  title={Genome packaging in influenza A virus.},
  author={Edward C Hutchinson and Johann C. von Kirchbach and Julia R. Gog and Paul Digard},
  journal={The Journal of general virology},
  year={2010},
  volume={91 Pt 2},
  pages={
          313-28
        }
}
The negative-sense RNA genome of influenza A virus is composed of eight segments, which encode 12 proteins between them. At the final stage of viral assembly, these genomic virion (v)RNAs are incorporated into the virion as it buds from the apical plasma membrane of the cell. Genome segmentation confers evolutionary advantages on the virus, but also poses a problem during virion assembly as at least one copy of each of the eight segments is required to produce a fully infectious virus particle… CONTINUE READING

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References

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SHOWING 1-10 OF 141 REFERENCES

Orthomyxovirus replication, transcription, and polyadenylation.

  • Current topics in microbiology and immunology
  • 2004
VIEW 13 EXCERPTS
HIGHLY INFLUENTIAL

Selective incorporation of influenza virus RNA segments into virions.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2003
VIEW 14 EXCERPTS
HIGHLY INFLUENTIAL