Genome organization at different scales: nature, formation and function.

Abstract

Since the discovery of chromosome territories, it has been clear that DNA within the nucleus is spatially organized. During the last decade, a tremendous body of work has described architectural features of chromatin at different spatial scales, such as A/B compartments, topologically associating domains (TADs), and chromatin loops. These features correlate… (More)
DOI: 10.1016/j.ceb.2018.03.009

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