Genome mining and metabolic profiling of the rhizosphere bacterium Pseudomonas sp. SH-C52 for antimicrobial compounds

@inproceedings{Voort2015GenomeMA,
  title={Genome mining and metabolic profiling of the rhizosphere bacterium Pseudomonas sp. SH-C52 for antimicrobial compounds},
  author={Menno van der Voort and Harold J G Meijer and Yvonne Schmidt and Jeramie D Watrous and E. M. J. Dekkers and Rodrigo Mendes and Pieter C. Dorrestein and Harald Gross and Jos M. Raaijmakers},
  booktitle={Front. Microbiol.},
  year={2015}
}
The plant microbiome represents an enormous untapped resource for discovering novel genes and bioactive compounds. Previously, we isolated Pseudomonas sp. SH-C52 from the rhizosphere of sugar beet plants grown in a soil suppressive to the fungal pathogen Rhizoctonia solani and showed that its antifungal activity is, in part, attributed to the production of the chlorinated 9-amino-acid lipopeptide thanamycin (Mendes et al., 2011). To get more insight into its biosynthetic repertoire, the genome… CONTINUE READING
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