Genome instability in Lactobacillus rhamnosus GG.

  title={Genome instability in Lactobacillus rhamnosus GG.},
  author={Wilbert Sybesma and Douwe Molenaar and Wilfred F J van Ijcken and K Venema and Remco Kort},
  journal={Applied and environmental microbiology},
  volume={79 7},
We describe here a comparative genome analysis of three dairy product isolates of Lactobacillus rhamnosus GG (LGG) and the ATCC 53103 reference strain to the published genome sequence of L. rhamnosus GG. The analysis showed that in two of three isolates, major DNA segments were missing from the genomic islands LGGISL1,2. The deleted DNA segments consist of 34 genes in one isolate and 84 genes in the other and are flanked by identical insertion elements. Among the missing genes are the spaCBA… CONTINUE READING
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