Genome expression analysis of Anopheles gambiae: responses to injury, bacterial challenge, and malaria infection.

@article{Dimopoulos2002GenomeEA,
  title={Genome expression analysis of Anopheles gambiae: responses to injury, bacterial challenge, and malaria infection.},
  author={George Dimopoulos and George K. Christophides and Stephan Meister and Joerg Schultz and Kevin P. White and Carolina Barillas-Mury and Fotis C. Kafatos},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2002},
  volume={99 13},
  pages={8814-9}
}
The complex gene expression responses of Anopheles gambiae to microbial and malaria challenges, injury, and oxidative stress (in the mosquito and/or a cultured cell line) were surveyed by using cDNA microarrays constructed from an EST-clone collection. The expression profiles were broadly subdivided into induced and down-regulated gene clusters. Gram+ and Gram- bacteria and microbial elicitors up-regulated a diverse set of genes, many belonging to the immunity class, and the response to malaria… CONTINUE READING
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