Genome editing assessment using CRISPR Genome Analyzer (CRISPR-GA)

@article{Gell2014GenomeEA,
  title={Genome editing assessment using CRISPR Genome Analyzer (CRISPR-GA)},
  author={Marc G{\"u}ell and Luhan Yang and George M. Church},
  journal={Bioinformatics},
  year={2014},
  volume={30 20},
  pages={2968-70}
}
SUMMARY Clustered regularly interspaced short palindromic repeats (CRISPR)-based technologies have revolutionized human genome engineering and opened countless possibilities to basic science, synthetic biology and gene therapy. Albeit the enormous potential of these tools, their performance is far from perfect. It is essential to perform a posterior careful analysis of the gene editing experiment. However, there are no computational tools for genome editing assessment yet, and current… CONTINUE READING
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