Genome duplications of early vertebrates as a possible chronicle of the evolutionary history of the neural crest

@article{Wada2006GenomeDO,
  title={Genome duplications of early vertebrates as a possible chronicle of the evolutionary history of the neural crest},
  author={Hiroshi Wada and Kaz Makabe},
  journal={International Journal of Biological Sciences},
  year={2006},
  volume={2},
  pages={133 - 141}
}
It is now accepted that ancestral vertebrates underwent two rounds of genome duplication. Here we test the possible utility of these genome duplication events as a reference time for the evolutionary history of vertebrates, by tracing the molecular evolutionary history of the genes involved in vertebrate neural crest development. For most transcription factors that are involved in neural crest specification, more than two paralogs are involved in that process. These were likely involved in the… CONTINUE READING

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