Genome differences among field isolates and vaccine strains of pseudorabies virus.

@article{Gielkens1985GenomeDA,
  title={Genome differences among field isolates and vaccine strains of pseudorabies virus.},
  author={Arno L J Gielkens and J T van Oirschot and Anton J. M. Berns},
  journal={The Journal of general virology},
  year={1985},
  volume={66 ( Pt 1)},
  pages={69-82}
}
The DNA of field isolates and vaccine strains of pseudorabies virus (PRV) was analysed by digestion with the restriction endonuclease BamHI. A number of distinct restriction profiles of the field isolates obtained from different locations within Europe were observed. As for herpes simplex virus, the variations could be classified into two types: first, alterations in the mobility of fragments due to the presence of additional sequences and/or the occurrence of deletions, a phenomenon most… CONTINUE READING