Genome conformation capture reveals that the Escherichia coli chromosome is organized by replication and transcription

Abstract

To fit within the confines of the cell, bacterial chromosomes are highly condensed into a structure called the nucleoid. Despite the high degree of compaction in the nucleoid, the genome remains accessible to essential biological processes, such as replication and transcription. Here, we present the first high-resolution chromosome conformation capture… (More)
DOI: 10.1093/nar/gkt325

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