Genome-based insights into the resistomes and mobilomes of two Providencia rettgeri strains isolated from wound infections in Madagascar

  title={Genome-based insights into the resistomes and mobilomes of two Providencia rettgeri strains isolated from wound infections in Madagascar},
  author={Pierrette Landrie Simo Tchuinte and Mamitina Alain Noah Rabenandrasana and Lovasoa Ramparany and Elisoa Hariniana Ratsima and Vincent Enouf and Fr{\'e}d{\'e}rique Randrianirina and Jean-Marc Collard},
  journal={Journal of global antimicrobial resistance},
3 Citations

Isolation and genomic characterization of a pathogenic Providencia rettgeri strain G0519 in turtle Trachemys scripta.

This was first report on genomic characterization of multidrug-resistant pathogenic P. rettgeri in cultured turtles and the closest relationship was with P. heimbachae closer than with other Providencia spp.

Genomes of Gut Bacteria from Nasonia Wasps Shed Light on Phylosymbiosis and Microbe-Assisted Hybrid Breakdown

It is shown that bacterial genomes in Nasonia differ from other environments and harbor genes with unique functions that may regulate phylosymbiotic relationships, thus supporting a hologenomic tenet that the same members of the microbiome and the host genome impact phylosYmbiosis, hybrid breakdown, and speciation.



Phenotypic and molecular characterisations of carbapenem-resistant Acinetobacter baumannii strains isolated in Madagascar

Several virulence genes were found in the CRAb isolates, among which two genes, epsA and ptk, responsible for the capsule-positive phenotype, were involved in A. baumannii pathogenesis, highlighting the importance of better monitoring and controlling CRAb in Madagascan hospitals to avoid their spread.

Mobile Insertion Cassette Elements Found in Small Non-Transmissible Plasmids in Proteeae May Explain qnrD Mobilization

The conclusions are that the small non-transmissibleqnrD-plasmids described here may result from the recombination between an as-yet-unknown progenitor of qnrD and pVERM, and they can recombined with larger multiresistant plasmids conjugated in Proteeae.

Type II and type IV topoisomerase mutations in clinical isolates of Morganella morganii harbouring the qnrD gene

This is the first report in Tunisia of qnrD determinant and tow new gyrB muations in M. morganii, and the nosocomial infection due to this proteeae invites further study of its epidemiologic evolution.

pMdT1, a small ColE1-like plasmid mobilizing a new variant of the aac(6')-Ib-cr gene in Salmonella enterica serovar Typhimurium.

The pMdT1 is the smallest mobilizable ColE1-like plasmid containing an aac(6')-Ib-cr gene that has been described so far, and also decreased susceptibility to ciprofloxacin and norfloxACin in the transformant strain, as MICs demonstrated.

Classes 1 and 2 integrons in faecal Escherichia coli strains isolated from mother-child pairs in Nigeria

Integrons are important determinants of resistance in faecal E. coli and there is a need for improved surveillance for resistance and its mechanisms of dissemination and persistence and mobility of resistance genes in the community and clinical settings.

ColE1-Like Plasmid pIP843 of Klebsiella pneumoniae Encoding Extended-Spectrum β-Lactamase CTX-M-17

Results of primer extension experiments indicated that ISEcp1 provides the promoter for expression of blaCTX-M-17 and may contribute to dissemination of this gene.

Mechanisms of drug resistance: quinolone resistance

The bacterial quinolone resistance armamentarium is large due to plasmid‐encoded resistance, one mutant aminoglycoside‐modifying enzyme that also modifies certain qu inolones, and mobile efflux pumps, and plasmids with these mechanisms often encode additional antimicrobial resistances and can transfer multidrug resistance that includes quinlones.

Benchmarking of methods for identification of antimicrobial resistance genes in bacterial whole genome data.

OBJECTIVES Next generation sequencing (NGS) may be an alternative to phenotypic susceptibility testing for surveillance and clinical diagnosis. However, current bioinformatics methods may be

Mobile Genetic Elements Associated with Antimicrobial Resistance

The characteristics of the major types of mobile genetic elements involved in acquisition and spread of antibiotic resistance in both Gram-negative and Gram-positive bacteria are outlined, focusing on the so-called ESKAPEE group of organisms, which have become the most problematic hospital pathogens.

In Silico Detection and Typing of Plasmids using PlasmidFinder and Plasmid Multilocus Sequence Typing

Two easy-to-use Web tools for in silico detection and characterization of whole-genome sequence (WGS) and whole-plasmid sequence data from members of the family Enterobacteriaceae are designed and developed.