Genome-based analysis of biosynthetic aminotransferase genes of Corynebacterium glutamicum.

  title={Genome-based analysis of biosynthetic aminotransferase genes of Corynebacterium glutamicum.},
  author={Alice C. McHardy and Andreas Tauch and Christian R{\"u}ckert and Alfred P{\"u}hler and J{\"o}rn Kalinowski},
  journal={Journal of biotechnology},
  volume={104 1-3},
Due to broad and overlapping substrate specificities, aminotransferases remain the last uncharacterized enzymes from most amino acid biosynthetic pathways in Corynebacterium glutamicum. We report here a complete description of all aminotransferases participating in the biosynthesis of the branched-chain amino acids and phenylalanine in C. glutamicum. We used methods of profile analysis on the newly available genome sequence to systematically search for and characterize members of the four known… CONTINUE READING
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