Genome and epigenome of a novel marine Thaumarchaeota strain suggest viral infection, phosphorothioation DNA modification and multiple restriction systems.

@article{Ahlgren2017GenomeAE,
  title={Genome and epigenome of a novel marine Thaumarchaeota strain suggest viral infection, phosphorothioation DNA modification and multiple restriction systems.},
  author={Nathan A. Ahlgren and Yangyang Chen and D. M. Needham and Alma E Parada and Rohan Sachdeva and Vickie Trinh and Ting Chen and Jed A. Fuhrman},
  journal={Environmental microbiology},
  year={2017},
  volume={19 6},
  pages={
          2434-2452
        }
}
Marine Thaumarchaeota are abundant ammonia-oxidizers but have few representative laboratory-cultured strains. We report the cultivation of Candidatus Nitrosomarinus catalina SPOT01, a novel strain that is less warm-temperature tolerant than other cultivated Thaumarchaeota. Using metagenomic recruitment, strain SPOT01 comprises a major portion of Thaumarchaeota (4-54%) in temperate Pacific waters. Its complete 1.36 Mbp genome possesses several distinguishing features: putative phosphorothioation… CONTINUE READING