Genome-Wide and Differential Proteomic Analysis of Hepatitis B Virus and Aflatoxin B1 Related Hepatocellular Carcinoma in Guangxi, China

@inproceedings{Qi2013GenomeWideAD,
  title={Genome-Wide and Differential Proteomic Analysis of Hepatitis B Virus and Aflatoxin B1 Related Hepatocellular Carcinoma in Guangxi, China},
  author={Lu-Nan Qi and Le-qun Li and Yuan-Yuan Chen and Zhao-hong Chen and Tao Bai and Bang-de Xiang and Xiao Mei Qin and Kai-yin Xiao and Min-Hao Peng and Zhi-ming Liu and Tang-wei Liu and Xue Qin and Shan Li and Ze-guang Han and Zeng-nan Mo and Regina M. Santella and Cheryl A. Winkler and Stephen J. O’Brien and Tao Peng},
  booktitle={PloS one},
  year={2013}
}
Both hepatitis B virus (HBV) and aflatoxin B1 (AFB1) exposure can cause liver damage as well as increase the probability of hepatocellular carcinoma (HCC). To investigate the underlying genetic changes that may influence development of HCC associated with HBV infection and AFB1 exposure, HCC patients were subdivided into 4 groups depending upon HBV and AFB1 exposure status: (HBV(+)/AFB1(+), HBV(+)/AFB1(-), HBV(-)/AFB1(+), HBV(-)/AFB1(-)). Genetic abnormalities and protein expression profiles… CONTINUE READING

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