Genome-Wide Scan Identifies Variant in TNFSF13 Associated with Serum IgM in a Healthy Chinese Male Population

@inproceedings{Yang2012GenomeWideSI,
  title={Genome-Wide Scan Identifies Variant in TNFSF13 Associated with Serum IgM in a Healthy Chinese Male Population},
  author={Ming Yang and Yongming Wu and Yanmei Lu and Changyuan Liu and Jielin Sun and Ming Xing Liao and Min Qin and Linjian Mo and Yong Gao and Zheng Mao Lu and Chunlei Wu and Youjie Zhang and Haiying Zhang and Xue Qin and Yan-ling Hu and Shijun Zhang and Jianling Li and Min Dong and S{\'i}qun Lilly Zheng and Jianfeng Xu and Xiaobo Yang and Aihua Tan and Zengnan Mo},
  booktitle={PloS one},
  year={2012}
}
IgM provides a first line of defense during microbial infections. Serum IgM levels are detected routinely in clinical practice. And IgM is a genetically complex trait. We conducted a two-stage genome-wide association study (GWAS) to identify genetic variants affecting serum IgM levels in a Chinese population of 3495, including 1999 unrelated subjects in the… CONTINUE READING