Genome-Wide Identification of Human RNA Editing Sites by Parallel DNA Capturing and Sequencing

@article{Li2009GenomeWideIO,
  title={Genome-Wide Identification of Human RNA Editing Sites by Parallel DNA Capturing and Sequencing},
  author={Jin Billy Li and Erez Y. Levanon and Jung-ki Yoon and John Aach and Bin Xie and Emily M. Leproust and Kun Zhang and Yuan Gao and George M. Church},
  journal={Science},
  year={2009},
  volume={324},
  pages={1210 - 1213}
}
Editing Expectations Although genetic information is stored in DNA, and faithfully copied into RNA, the cell can make the odd (and occasionally vitally important) change to the meaning of code during a process known as RNA editing. Thirteen edited genes are known in the nonrepetitive portion of the human genome, but the overall prevalence of RNA editing is unclear. Li et al. (p. 1210), used an unbiased genome-wide approach to identify 239 sites (in 207 target genes), with stringent criteria for… 
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