Genome-Wide Evolutionary Analysis of Eukaryotic DNA Methylation

@article{Zemach2010GenomeWideEA,
  title={Genome-Wide Evolutionary Analysis of Eukaryotic DNA Methylation},
  author={Assaf Zemach and Ivy E. McDaniel and Pedro Silva and D. Zilberman},
  journal={Science},
  year={2010},
  volume={328},
  pages={916 - 919}
}
  • Assaf Zemach, Ivy E. McDaniel, +1 author D. Zilberman
  • Published 2010
  • Biology, Medicine
  • Science
  • Epigenetic Maps Methylation of genomic DNA on cytosine bases provides critical epigenetic regulation of gene expression and is involved in silencing transposable elements (TEs) and repeated sequences, as well as regulating imprinted gene expression. Zemach et al. (p. 916, published online 15 April; see the Perspective by Jeltsch) analyzed DNA methylation in the genomes of five plants, five fungi, and seven animals by bisulfite sequencing. The data suggest that land plants and vertebrates, which… CONTINUE READING

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