Genome-Wide Dynamics of Nascent Noncoding RNA Transcription in Porcine Heart After Myocardial Infarction.

@article{Kaikkonen2017GenomeWideDO,
  title={Genome-Wide Dynamics of Nascent Noncoding RNA Transcription in Porcine Heart After Myocardial Infarction.},
  author={Minna U Kaikkonen and Paavo J. Halonen and Oscar Hsin-Fu Liu and Tiia A Turunen and Juho Pajula and Pierre Moreau and Ilakya Selvarajan and Tomi Tuomainen and Einari Aavik and Pasi Tavi and Seppo Yl{\"a}-Herttuala},
  journal={Circulation. Cardiovascular genetics},
  year={2017},
  volume={10 3}
}
BACKGROUND Microarrays and RNA sequencing are widely used to profile transcriptome remodeling during myocardial ischemia. However, the steady-state RNA analysis lacks in sensitivity to detect all noncoding RNA species and does not provide separation between transcriptional and post-transcriptional regulations. Here, we provide the first comprehensive analysis of nascent RNA profiles of mRNAs, primary micro-RNAs, long noncoding RNAs, and enhancer RNAs in a large animal model of acute infarction… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 7 times over the past 90 days. VIEW TWEETS
3 Extracted Citations
50 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.

Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 50 references

Similar Papers

Loading similar papers…