Genome-Wide Association Study of Relative Telomere Length

  title={Genome-Wide Association Study of Relative Telomere Length},
  author={Jennifer Prescott and Peter Kraft and Daniel Chasman and Sharon A Savage and Lisa Mirabello and Sonja I. Berndt and Joel L. Weissfeld and Jiali Han and Richard B Hayes and Stephen J. Chanock and David J. Hunter and Immaculata De Vivo},
  booktitle={PloS one},
Telomere function is essential to maintaining the physical integrity of linear chromosomes and healthy human aging. The probability of forming proper telomere structures depends on the length of the telomeric DNA tract. We attempted to identify common genetic variants associated with log relative telomere length using genome-wide genotyping data on 3,554 individuals from the Nurses' Health Study and the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial that took part in the… CONTINUE READING
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