Genome-Wide Association Study of Inattention and Hyperactivity–Impulsivity Measured as Quantitative Traits
@article{Ebejer2013GenomeWideAS,
title={Genome-Wide Association Study of Inattention and Hyperactivity–Impulsivity Measured as Quantitative Traits},
author={Jane L. Ebejer and David L. Duffy and Julius H. J. van der Werf and Margaret J. Wright and Grant W. Montgomery and Nathan A. Gillespie and Ian B. Hickie and Nicholas G. Martin and Sarah E. Medland},
journal={Twin Research and Human Genetics},
year={2013},
volume={16},
pages={560 - 574}
}Genome-wide association studies (GWAS) of attention-deficit/hyperactivity disorder (ADHD) offer the benefit of a hypothesis-free approach to measuring the quantitative effect of genetic variants on affection status. Generally the findings of GWAS relying on ADHD status have been non-significant, but the one study using quantitative measures of symptoms found SLC9A9 and SLC6A1 were associated with inattention and hyperactivity–impulsivity. Accordingly, we performed a GWAS using quantitative…
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