Genome-Wide Association Study of Copy Number Variations in Patients with Familial Neurocardiogenic Syncope

@article{Demir2016GenomeWideAS,
  title={Genome-Wide Association Study of Copy Number Variations in Patients with Familial Neurocardiogenic Syncope},
  author={Emre Demir and Can Hasdemir and H. Levent Ak and Sevcan Atay and Hikmet Hakan Aydin},
  journal={Biochemical Genetics},
  year={2016},
  volume={54},
  pages={487-494}
}
Neurocardiogenic syncope (NCS) is the most frequent type of syncope characterized by a self-limited episode of systemic hypotension. In this study, we conducted the first genome-wide association study testing copy number variations for association with NCS. Study population consisted of 107 consecutive patients with recurrent syncope and positive head-up tilt table testing. Four families with NCS were selected for CNV analysis. Affymetrix GeneChip® SNP 6.0 array was used for CNV analysis. Data… CONTINUE READING