Genome-Wide Association Study Identifies Cxcl Family Members as Partial Mediators of LPS-induced Periodontitis.

Abstract

Periodontitis (PD) is characterized by bacterial infection and inflammation of tooth supporting structures and can lead to tooth loss. PD affects ∼47% of the U.S. population over 30 and has a heritability of about 50%. While the host immunoinflammatory response and genetic background play a role, little is known of the underlying genetic factors. We… (More)
DOI: 10.1002/jbmr.3440

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