Genome-Wide Association Study Confirming Association of HLA-DP with Protection against Chronic Hepatitis B and Viral Clearance in Japanese and Korean

@inproceedings{Nishida2012GenomeWideAS,
  title={Genome-Wide Association Study Confirming Association of HLA-DP with Protection against Chronic Hepatitis B and Viral Clearance in Japanese and Korean},
  author={Nao Nishida and Hiromi Sawai and Kentaro Matsuura and M Sugiyama and Sang Hoon Ahn and Jun Yong Park and Shuhei Hige and J. Kang and Kazuyuki Suzuki and Masayuki Kurosaki and Yasuhiro Asahina and Satoshi Mochida and Masaaki Watanabe and Eiji Tanaka and Masao Honda and Shuichi Kaneko and Etsuro Orito and Yoshito Itoh and Eiji Mita and A Tamori and Yoshikazu Murawaki and Yoichi Hiasa and Isao Sakaida and Masaaki Korenaga and Keisuke Hino and Tatsuya Ide and Minae Kawashima and Yoriko Mawatari and Megumi Sageshima and Yuko Ogasawara and Asako Koike and Namiki Izumi and Kwang-hyub Han and Yasuhito Tanaka and Katsushi Tokunaga and Masashi Mizokami},
  booktitle={PloS one},
  year={2012}
}
Hepatitis B virus (HBV) infection can lead to serious liver diseases, including liver cirrhosis (LC) and hepatocellular carcinoma (HCC); however, about 85-90% of infected individuals become inactive carriers with sustained biochemical remission and very low risk of LC or HCC. To identify host genetic factors contributing to HBV clearance, we conducted genome-wide association studies (GWAS) and replication analysis using samples from HBV carriers and spontaneously HBV-resolved Japanese and… CONTINUE READING
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