Genome-Wide Association Analysis of Oxidative Stress Resistance in Drosophila melanogaster

@inproceedings{Weber2012GenomeWideAA,
  title={Genome-Wide Association Analysis of Oxidative Stress Resistance in Drosophila melanogaster},
  author={Allison L. Weber and George F. Khan and Michael M. Magwire and Crystal L. Tabor and Trudy F. C. Mackay and Robert R. H. Anholt},
  booktitle={PloS one},
  year={2012}
}
BACKGROUND Aerobic organisms are susceptible to damage by reactive oxygen species. Oxidative stress resistance is a quantitative trait with population variation attributable to the interplay between genetic and environmental factors. Drosophila melanogaster provides an ideal system to study the genetics of variation for resistance to oxidative stress. METHODS AND FINDINGS We used 167 wild-derived inbred lines of the Drosophila Genetic Reference Panel for a genome-wide association study of… CONTINUE READING
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