Genome-Wide Analysis of the Binding of the Hox Protein Ultrabithorax and the Hox Cofactor Homothorax in Drosophila

@article{Choo2011GenomeWideAO,
  title={Genome-Wide Analysis of the Binding of the Hox Protein Ultrabithorax and the Hox Cofactor Homothorax in Drosophila},
  author={S. Choo and Robert White and S. Russell},
  journal={PLoS ONE},
  year={2011},
  volume={6}
}
Hox genes encode a family of transcription factors that are key developmental regulators with a highly conserved role in specifying segmental diversity along the metazoan body axis. Although they have been shown to regulate a wide variety of downstream processes, direct transcriptional targets have been difficult to identify and this has been a major obstacle to our understanding of Hox gene function. We report the identification of genome-wide binding sites for the Hox protein Ultrabithorax… Expand
Genomic approaches to understanding Hox gene function.
The regulation of Hox genes by microRNAs during Drosophila development
Roles of cofactors and chromatin accessibility in Hox protein target specificity
Mechanisms of Specificity for Hox Factor Activity
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 91 REFERENCES
The UBX-regulated network in the haltere imaginal disc of D. melanogaster.
Hox gene Ultrabithorax regulates distinct sets of target genes at successive stages of Drosophila haltere morphogenesis
A structural model for a homeotic protein-extradenticle-DNA complex accounts for the choice of HOX protein in the heterodimer.
  • S. Chan, R. Mann
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 1996
Shaping segments: Hox gene function in the genomic age
  • S. D. Hueber, I. Lohmann
  • Biology, Medicine
  • BioEssays : news and reviews in molecular, cellular and developmental biology
  • 2008
Stability and Dynamics of Polycomb Target Sites in Drosophila Development
Hox specificity unique roles for cofactors and collaborators.
...
1
2
3
4
5
...