Genome-Wide Analysis of Wilms' Tumor 1-Controlled Gene Expression in Podocytes Reveals Key Regulatory Mechanisms.

@article{Kann2015GenomeWideAO,
  title={Genome-Wide Analysis of Wilms' Tumor 1-Controlled Gene Expression in Podocytes Reveals Key Regulatory Mechanisms.},
  author={Martin Kann and Sandrine Ettou and Youngsook L. Jung and Maximilian O Lenz and Mary E Taglienti and Peter J. Park and Bernhard Schermer and Thomas Benzing and Jordan A. Kreidberg},
  journal={Journal of the American Society of Nephrology : JASN},
  year={2015},
  volume={26 9},
  pages={2097-104}
}
The transcription factor Wilms' tumor suppressor 1 (WT1) is key to podocyte development and viability; however, WT1 transcriptional networks in podocytes remain elusive. We provide a comprehensive analysis of the genome-wide WT1 transcriptional network in podocytes in vivo using chromatin immunoprecipitation followed by sequencing (ChIPseq) and RNA… CONTINUE READING