Genome-Scale Identification of Nucleosome Positions in S. cerevisiae

@article{Yuan2005GenomeScaleIO,
  title={Genome-Scale Identification of Nucleosome Positions in S. cerevisiae},
  author={Guocheng Yuan and Yuen-Jong Liu and Michael F. Dion and Michael D Slack and Lani F. Wu and Steven J. Altschuler and Oliver J. Rando},
  journal={Science},
  year={2005},
  volume={309},
  pages={626 - 630}
}
The positioning of nucleosomes along chromatin has been implicated in the regulation of gene expression in eukaryotic cells, because packaging DNA into nucleosomes affects sequence accessibility. We developed a tiled microarray approach to identify at high resolution the translational positions of 2278 nucleosomes over 482 kilobases of Saccharomyces cerevisiae DNA, including almost all of chromosome III and 223 additional regulatory regions. The majority of the nucleosomes identified were well… Expand
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