Genome-Scale Identification of Legionella pneumophila Effectors Using a Machine Learning Approach

@inproceedings{Burstein2009GenomeScaleIO,
  title={Genome-Scale Identification of Legionella pneumophila Effectors Using a Machine Learning Approach},
  author={David Burstein and Tal Zusman and Elena Degtyar and R. I. Viner and Gil Segal and Tal Pupko},
  booktitle={PLoS pathogens},
  year={2009}
}
A large number of highly pathogenic bacteria utilize secretion systems to translocate effector proteins into host cells. Using these effectors, the bacteria subvert host cell processes during infection. Legionella pneumophila translocates effectors via the Icm/Dot type-IV secretion system and to date, approximately 100 effectors have been identified by… CONTINUE READING