Genome Instability in Lactobacillus rhamnosus GG

  title={Genome Instability in Lactobacillus rhamnosus GG},
  author={W. Sybesma and D. Molenaar and W. V. van Ijcken and K. Venema and R. Kort},
  journal={Applied and Environmental Microbiology},
  pages={2233 - 2239}
  • W. Sybesma, D. Molenaar, +2 authors R. Kort
  • Published 2013
  • Biology, Medicine
  • Applied and Environmental Microbiology
  • ABSTRACT We describe here a comparative genome analysis of three dairy product isolates of Lactobacillus rhamnosus GG (LGG) and the ATCC 53103 reference strain to the published genome sequence of L. rhamnosus GG. The analysis showed that in two of three isolates, major DNA segments were missing from the genomic islands LGGISL1,2. The deleted DNA segments consist of 34 genes in one isolate and 84 genes in the other and are flanked by identical insertion elements. Among the missing genes are the… CONTINUE READING
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