Genome Growth and the Evolution of the Genotype-Phenotype Map

@inproceedings{Altenberg1995GenomeGA,
  title={Genome Growth and the Evolution of the Genotype-Phenotype Map},
  author={Lee Altenberg},
  booktitle={Evolution and Biocomputation},
  year={1995}
}
The evolution of new genes is distinct from evolution through allelic substitution in that new genes bring with them new degrees of freedom for genetic variability. Selection in the evolution of new genes can therefore act to sculpt the dimensions of variability in the genome. This “constructional” selection effect is an evolutionary mechanism, in addition to genetic modification, that can affect the variational properties of the genome and its evolvability. One consequence of selective genome… CONTINUE READING
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References

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Showing 1-10 of 102 references

Adaptation on rugged fitness landscapes

  • S. A. Kauffman
  • D. Stein, editor, Lectures in the Sciences of…
  • 1989
Highly Influential
10 Excerpts

Principles of adaptation in complex systems

  • S. A. Kauffman
  • D. Stein, editor, Lectures in the Sciences of…
  • 1989
Highly Influential
5 Excerpts

Exon shuffling: A prediction of an excess of 0mod3 lengths for exons

  • L. Altenberg
  • Letter to Nature. Unpublished.
  • 1983
Highly Influential
7 Excerpts

Knowledge representation in the genome: new genes, exons, and pleiotropy

  • L. Altenberg
  • Genetics 110, supplement: s41. Abstract of paper…
  • 1985
Highly Influential
3 Excerpts

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