Genital herpes

  title={Genital herpes},
  author={Rachna Gupta and Terri J Warren and Anna Wald},
  journal={The Lancet},
54 Citations
Bioactive Compounds as Potential Agents for Sexually Transmitted Diseases Management: A Review to Explore Molecular Mechanisms of Action
It is concluded that natural compounds may be a significant source for adjuvant drugs / complementary therapies in the treatment of STDs and the future must conduct extensive clinical trials and the development of pharmaceutical nanotechnologies for a greater therapeutic effect. Expand
Drug Resistance in Reproductive Diseases
The effect of drug resistance on reproductive system diseases is discussed and various aspects of resistance, possible alternatives, and future directions related to drug resistance are evaluated. Expand
Epidemiology of herpes simplex virus type 2 in Asia: A systematic review, meta-analysis, and meta-regression
Findings support the need for an HSV-2 vaccine and universal access to sexual and reproductive health services in Asia and support the decline in seroprevalence over the last three decades. Expand
Epidemiology of herpes simplex virus type 2 in sub-Saharan Africa: Systematic review, meta-analyses, and meta-regressions
Temporal declines and geographic distribution of HSV-2 seroprevalence mirror that of HIV prevalence, suggesting sexual risk behavior has been declining for three decades. Expand
Harringtonine Inhibits Herpes Simplex Virus Type 1 Infection by Reducing Herpes Virus Entry Mediator Expression
Harringtonine showed antiviral activity against HSV-1 and ACV-resistant strains by targeting HVEM and could be a promising therapeutic candidate for mitigating HSv-1-induced-pathogenesis. Expand
L’herpès génital
La prise en charge therapeutique de l’herpes genital repose essentiellement sur des traitements antiviraux par le valaciclovir, medicament tres actif and tres peu toxique pour prevenir cette infection virale. Expand
Pathogenesis and virulence of herpes simplex virus.
  • Shuyong Zhu, Abel Viejo-Borbolla
  • Medicine
  • Virulence
  • 2021
The HSV life cycle, the interaction of HSV with the immune system and three of the best-studied pathologies are reviewed, including Herpes stromal keratitis, herpes simplex encephalitis and genital herpes. Expand
Potential of mucoadhesive chitosan glutamate microparticles as microbicide carriers – antiherpes activity and penetration behavior across the human vaginal epithelium
Ex vivo penetration studies revealed that gCS increased the accumulation of active agent in the vaginal epithelium but surprisingly did not facilitate its penetration across human tissue, and obtained antiviral results demonstrated the potential of gCS as an antiherpes adjunctive, whose mode of action was related to blocking viral attachment. Expand