Genital herpes

@article{Gupta2008GenitalH,
  title={Genital herpes},
  author={Rachna Gupta and Terri J Warren and Anna Wald},
  journal={The Lancet},
  year={2008},
  volume={370},
  pages={2127-2137}
}

Herpes simplex virus type 2 inhibits TNF-α-induced NF-κB activation through viral protein ICP22-mediated interaction with p65

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The HSV life cycle, the interaction of HSV with the immune system and three of the best-studied pathologies are reviewed, including Herpes stromal keratitis, herpes simplex encephalitis and genital herpes.

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Ex vivo penetration studies revealed that gCS increased the accumulation of active agent in the vaginal epithelium but surprisingly did not facilitate its penetration across human tissue, and obtained antiviral results demonstrated the potential of gCS as an antiherpes adjunctive, whose mode of action was related to blocking viral attachment.
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