Genital grooming and emesis induced by vanilloids in Suncus murinus, the house musk shrew.

@article{Rudd2001GenitalGA,
  title={Genital grooming and emesis induced by vanilloids in Suncus murinus, the house musk shrew.},
  author={John A Rudd and Man K. Wai},
  journal={European journal of pharmacology},
  year={2001},
  volume={422 1-3},
  pages={185-95}
}
The potential of resiniferatoxin and capsaicin to modulate emesis and genital grooming was investigated in Suncus murinus. Resinifertoxin (3-30 nmol, i.c.v.), E-capsaicin (10-100 nmol, i.c.v.) and Z-capsaicin (100 nmol, i.c.v.) induced emesis (P<0.05) and subsequently antagonised the emetic response induced by intragastric copper sulphate (480.6 micromol/kg; P<0.05). However, resiniferatoxin failed to affect nicotine-induced (30.7 mol/kg, s.c.) emesis (P>0.05). Only resiniferatoxin induced… CONTINUE READING

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