Genistein impairs early testosterone production in fetal mouse testis via estrogen receptor alpha.

@article{Lehraiki2011GenisteinIE,
  title={Genistein impairs early testosterone production in fetal mouse testis via estrogen receptor alpha.},
  author={Abdelali Lehraiki and Cathie Chamaillard and Andr{\'e}e Krust and Ren{\'e} Habert and Christine Levacher},
  journal={Toxicology in vitro : an international journal published in association with BIBRA},
  year={2011},
  volume={25 8},
  pages={1542-7}
}
The widespread consumption of soy-based products raises the issue of the reproductive toxicity of phytoestrogens. Indeed, it is well known that genistein, an isoflavone found in soybeans and soy products, mimics the actions of estrogens and that the fetal testis is responsive to estrogens. Therefore we investigated whether genistein could have deleterious… CONTINUE READING