Genistein affects adipose tissue deposition in a dose-dependent and gender-specific manner.

  title={Genistein affects adipose tissue deposition in a dose-dependent and gender-specific manner.},
  author={Marialetizia Penza and Claudia Montani and Annalisa Romani and Pamela Vignolini and Barbara Pampaloni and Annalisa Tanini and Maria Luisa Brandi and Paloma Alonso-Magdalena and Angel Nadal and L Ottobrini and Ornella Parolini and Eliana Bignotti and Stefano Calza and Adriana C Maggi and Pier Giovanni Grigolato and Diego Di Lorenzo},
  volume={147 12},
The soy isoflavone genistein targets adipose tissue and elicits physiological effects that may vary based on dietary intake. We hypothesized that the adipose effects of genistein are dose and gender dependent. Four-week-old C57BL/6 male and female mice received daily oral doses of genistein (50-200,000 microg/kg.d) or 17beta-estradiol (E2) (5 microg/kg.d) for 15 d or a diet containing 800 ppm genistein. Genistein increased epididymal and renal fat pad and adipocyte size at doses up to 50,000… CONTINUE READING


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Effect of Genistein on Adipose Tissue Deposition Downloaded from by guest on 24 January 2018

  • Y Naito, K Uchiyama, +4 authors Ichikawa
  • Endocrinology,
  • 2006

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