Genistein Mediated Molecular Pharmacology, Cell-Specific Anti-Breast Cancer Mechanism with Synergistic Effect and in silico Safety Measurement

@inproceedings{Sohel2021GenisteinMM,
  title={Genistein Mediated Molecular Pharmacology, Cell-Specific Anti-Breast Cancer Mechanism with Synergistic Effect and in silico Safety Measurement},
  author={Md Mahmodul Hasan Sohel and Partha Biswas and Md. Al Amin and Dipta Dey and Habiba Sultana and Suraiya Aktar and Md. Sharif Khan and Md. Arju Hossain and Priyanka Paul and Nurul M Islam and M. Rahman and Bonglee Kim and Abdullah Al Mamun},
  year={2021}
}
Breast cancer (BC) is the most common type of cancer in both men and women alike, but it is more prevalent in women. Natural compounds that can modulate the oncogenic process can be considered a significant anti-cancer agent for treating BC. These natural compounds are more effective than synthetic drugs, which have profound side effects on the normal cell and resistance to cancer cells. Genistein is a type of dietary phytoestrogen included in the flavonoid group with a similar structure of… 
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It is summarized that this phytoestrogen suppressed NF-κB, STAT, MAPK, and PIK/AKT signaling pathways and activated some tumor suppressor protein in numerous breast cancer models and exhibited promising pharmacokinetics properties with less toxicity in the bodies.

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TLDR
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