Geniposide, a novel agonist for GLP-1 receptor, prevents PC12 cells from oxidative damage via MAP kinase pathway.

@article{Liu2007GeniposideAN,
  title={Geniposide, a novel agonist for GLP-1 receptor, prevents PC12 cells from oxidative damage via MAP kinase pathway.},
  author={Jianhui Liu and Fei Yin and Xuxu Zheng and Jiajia Jing and Yinhe Hu},
  journal={Neurochemistry international},
  year={2007},
  volume={51 6-7},
  pages={361-9}
}
Alzheimer's disease (AD) is the most common form of dementia. Glucagon-like peptide-1 (GLP-1) gives a new genre in therapeutic targets for intervention in AD with its neurotrophic and neuroprotective functions. In previous work, we identified that geniposide is a novel agonist for GLP-1 receptor, which shows neurotrophic characteristics to induce the… CONTINUE READING