Genipin Inhibits Mitochondrial Uncoupling Protein 2 Expression and Ameliorates Podocyte Injury in Diabetic Mice

@inproceedings{Qiu2012GenipinIM,
  title={Genipin Inhibits Mitochondrial Uncoupling Protein 2 Expression and Ameliorates Podocyte Injury in Diabetic Mice},
  author={Wenjing Qiu and Yang Zhou and Lei Jiang and Li Fang and Lu Chen and Weifang Su and Ruoyun Tan and Chen-Yu Zhang and Xiao Han and Junwei Yang},
  booktitle={PloS one},
  year={2012}
}
Diabetic nephropathy (DN) is one of the most common causes of end stage renal disease (ESRD) in China, which requires renal replacement therapy. Recent investigations have suggested an essential role of podocyte injury in the initial stage of DN. This study investigated the potential therapeutic role of genipin, an active extract from a traditional Chinese… CONTINUE READING