Genetics pathogenesis in the ovarian insufficiency

Abstract

Premature Ovarian Failure (POF) is a heterogeneous syndrome characterized by Hypergonadotropic. Hypogonadism that affects about 1% of women younger than 40 years old, while an incidence of 1/1000 is reported in women younger than 30 years old [1]. This hormonal disorder is caused by the loss of the ovarian response towards the pituitary gonadrotropins… (More)

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