Genetics of type 2 diabetes: pathophysiologic and clinical relevance
@article{Herder2011GeneticsOT, title={Genetics of type 2 diabetes: pathophysiologic and clinical relevance}, author={Christian Herder and Michael Roden}, journal={European Journal of Clinical Investigation}, year={2011}, volume={41} }
Eur J Clin Invest 2011; 41 (6): 679–692
173 Citations
Beta cell stress in a 4‐year follow‐up of patients with type 2 diabetes: A longitudinal analysis of the BetaDecline Study
- Medicine, BiologyDiabetes/metabolism research and reviews
- 2018
Type 2 diabetes mellitus (T2DM) is associated with a progressive deterioration in beta cell function and loss of glycaemic control. Clinical predictors of beta cell failure are needed to guide…
Newly diagnosed diabetes - treatment plan and goals
- Medicine
- 2018
This video explains how the pancreas of people with diabetes change the whole dynamic of their lives as a result of the disease.
Allgemeine Grundlagen des Diabetes mellitus
- Medicine
- 2014
Nach Schatzungen der International Diabetes Federation hatten im Jahr 2011 366 Mio. Personen im Alter zwischen 20 und 79 Jahren weltweit einen Diabetes mellitus.
A Longitudinal Study of Diabetes Mellitus : With Special Reference to Incidence and Prevalence, and to Determinants of Macrovascular Complications and Mortality
- Medicine
- 2014
Objectives. To investigate diabetes prevalence, incidence, mortality trends, the effects of hyperglycaemia and blood pressure, diabetes and hypertension treatment, and the effect of screening detec…
Personalized medicine in Type 2 Diabetes
- Medicine, BiologyBioMedicine
- 2014
Effect of genetic profiling on T2D and its complications, pharmacogenetics and pharmacogenomics of oral anitdiabetic drug will be explored and genetic association studies have shown polymorphisms at specific loci may help identify individuals at greatest risk and response to oral antidiabetic drugs.
Type 2 diabetes across generations: from pathophysiology to prevention and management
- Medicine, BiologyThe Lancet
- 2011
Interacción genoma-ambiente en la diabetes mellitus tipo 2
- Medicine
- 2018
Type 2 diabetes mellitus is more likely to appear when genetic and environmental factors coincide because it is a multifactorial disease in which the presence of genetic factors is not enough, but the action of a predisposing environment is required to appear.
Role of vitamin D receptor (VDR) genetic polymorphism in onset of type 2 diabetes mellitus: A Review
- Biology, MedicineJournal of Bioscience and Biotechnology Discovery
- 2019
The present review will focus on concept that polymorphism of VDR gene may has role in susceptibilty of onset of T2DM and its pathogenesises.
Sfrp5 associates with beta‐cell function in humans
- Biology, MedicineEuropean journal of clinical investigation
- 2016
The aim of the study was to characterize the associations between serum Sfrp5 and indices of insulin sensitivity and beta‐cell function from dynamic measurements using oral glucose tolerance tests (OGTT) in humans.
Microbial Regulation of Glucose Metabolism and Insulin Resistance
- Biology, MedicineGenes
- 2017
This review aims to generate a deeper understanding of the underlying mechanism of potential microbial strains, which can be used as probiotics in type 2 diabetes patients, to elucidate the complex interaction of gut microbiota, intestinal permeability and inflammation.
References
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