Genetics of suicide

  title={Genetics of suicide},
  author={Brigitta Bondy and Andreas B{\"u}ttner and Peter Zill},
  journal={Molecular Psychiatry},
The concept that genetic factors contribute to the complex trait of suicidal behaviour has stimulated much work aimed at identifying susceptibility genes. So far molecular genetic studies focused on the serotonergic pathway as the intent to die and the lethality of suicide acts were related to the serotonergic system. Two genes have so far emerged as being involved in the vulnerability for suicidality: first, the intronic polymorphisms (A218C or A779C) of the tryptophan hydroxylase 1 (TPH1… CONTINUE READING
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