Genetics of stroke: a review of recent advances.

@article{DominguesMontanari2008GeneticsOS,
  title={Genetics of stroke: a review of recent advances.},
  author={Sophie Domingues-Montanari and Maite Mendioroz and Alberto del R{\'i}o-Esp{\'i}nola and Israel Fern{\'a}ndez-Cadenas and J Montaner},
  journal={Expert review of molecular diagnostics},
  year={2008},
  volume={8 4},
  pages={
          495-513
        }
}
Stroke is a multifactorial disease responsible for nearly 10% of deaths each year in industrialized countries. While some monogenic forms of stroke have been described, the vast majority result from the common polygenic form of the disease. Progress in molecular genetics has allowed the identification, through genome-wide linkage analysis, of various candidate genes, including the genes encoding PDE4D and ALOX5AP. Since then, genetic research has been extensively performed from single candidate… CONTINUE READING

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