Genetics of rat neuroinflammation

  title={Genetics of rat neuroinflammation},
  author={Tomas Olsson and Ingrid Dahlman and Erik Wallstr{\"o}m and Robert Weissert and Fredrik Piehl},
  journal={Journal of Neuroimmunology},
The definition of genes regulating the pathogenetic pathways of autoimmune neuroinflammation, may provide targets for new therapeutic strategies. This is not easily accomplished in human disease. Such genetic dissection can more readily be done by the use of inbred rodent strains. With these, genetic heterogeneity is avoided and variation in the environmental influences is minimized. Close mimicking of the human disease characteristics is desirable in such endeavors. Chronic relapsing… CONTINUE READING


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